Willmund-lab

Research

Explore our lab’s research! We’ve been dedicated to advancing science and making significant discoveries. Below is a list of our publications. Take a look and see our work!

All

2023

Utilizing high‐resolution ribosome profiling for the global investigation of gene expression in <i>Chlamydomonas</i>
Utilizing high‐resolution ribosome profiling for the global investigation of gene expression in Chlamydomonas
Vincent Leon Gotsmann, Michael Kien Yin Ting, Nadin Haase, Sophia Rudorf, Reimo Zoschke, Felix Willmund
The Plant Journal  ·  04 Dec 2023  ·  doi:10.1111/tpj.16577
Networked proteins redundantly interact with VAP27 and RABG3 to regulate membrane tethering at the vacuole and beyond
Networked proteins redundantly interact with VAP27 and RABG3 to regulate membrane tethering at the vacuole and beyond
Sabrina Kaiser, Dietmar Mehlhorn, Paulina Ramirez Miranda, Fabian Ries, Frederik Sommer, Michael Schroda, Karin Schumacher, Felix Willmund, Christopher Grefen, David Scheuring
Cold Spring Harbor Laboratory  ·  29 Sep 2023  ·  doi:10.1101/2023.09.29.560113
Utilizing high resolution ribosome profiling for the global investigation of gene expression in<i>Chlamydomonas</i>
Utilizing high resolution ribosome profiling for the global investigation of gene expression inChlamydomonas
Vincent Leon Gotsmann, Michael Kien Yin Ting, Nadin Haase, Sophia Rudorf, Reimo Zoschke, Felix Willmund
Cold Spring Harbor Laboratory  ·  13 Feb 2023  ·  doi:10.1101/2023.02.13.528309
Competition co-immunoprecipitation reveals interactors of the chloroplast CPN60 chaperonin machinery
Competition co-immunoprecipitation reveals interactors of the chloroplast CPN60 chaperonin machinery
Fabian Ries, Heinrich Lukas Weil, Claudia Herkt, Timo Mühlhaus, Frederik Sommer, Michael Schroda, Felix Willmund
Cold Spring Harbor Laboratory  ·  05 Jan 2023  ·  doi:10.1101/2023.01.05.522938

2022

Structural features of chloroplast trigger factor determined at 2.6 Å resolution
Structural features of chloroplast trigger factor determined at 2.6 Å resolution
Yvonne Carius, Fabian Ries, Karin Gries, Oliver Trentmann, C. Roy D. Lancaster, Felix Willmund
Acta Crystallographica Section D Structural Biology  ·  27 Sep 2022  ·  doi:10.1107/S2059798322009068

2021

Systems approaches identify the consequences of monosomy in somatic human cells
Systems approaches identify the consequences of monosomy in somatic human cells
Narendra Kumar Chunduri, Paul Menges, Xiaoxiao Zhang, Angela Wieland, Vincent Leon Gotsmann, …, Jan O. Korbel, Felix Willmund, Maik Kschischo, Markus Raeschle, Zuzana Storchova
Nature Communications  ·  22 Sep 2021  ·  doi:10.1038/s41467-021-25288-x
Systems approaches identify the consequences of monosomy in somatic human cells
Systems approaches identify the consequences of monosomy in somatic human cells
Narendra Kumar Chunduri, Paul Menges, Vincent Leon Gotsmann, Xiaoxiao Zhang, Balca R. Mardin, …, Jan O. Korbel, Felix Willmund, Maik Kschischo, Markus Raeschle, Zuzana Storchova
Cold Spring Harbor Laboratory  ·  23 Feb 2021  ·  doi:10.1101/2021.02.22.432226

2020

CRISPR/Cas with ribonucleoprotein complexes and transiently selected telomere vectors allows highly efficient marker-free and multiple genome editing in Botrytis cinerea
CRISPR/Cas with ribonucleoprotein complexes and transiently selected telomere vectors allows highly efficient marker-free and multiple genome editing in Botrytis cinerea
Thomas Leisen, Fabian Bietz, Janina Werner, Alex Wegner, Ulrich Schaffrath, David Scheuring, Felix Willmund, Andreas Mosbach, Gabriel Scalliet, Matthias Hahn
PLOS Pathogens  ·  17 Aug 2020  ·  doi:10.1371/journal.ppat.1008326
CRISPR/Cas with ribonucleoprotein complexes and transiently selected telomere vectors allows highly efficient marker-free and multiple genome editing in<i>Botrytis cinerea</i>
CRISPR/Cas with ribonucleoprotein complexes and transiently selected telomere vectors allows highly efficient marker-free and multiple genome editing inBotrytis cinerea
Thomas Leisen, Fabian Bietz, Janina Werner, Alex Wegner, Ulrich Schaffrath, David Scheuring, Felix Willmund, Andreas Mosbach, Gabriel Scalliet, Matthias Hahn
Cold Spring Harbor Laboratory  ·  20 Jan 2020  ·  doi:10.1101/2020.01.20.912576

2019

The proteomic inventory reveals the chloroplast ribosome as nexus within a diverse protein network
The proteomic inventory reveals the chloroplast ribosome as nexus within a diverse protein network
Lisa Désirée Westrich, Vincent Leon Gotsmann, Claudia Herkt, Fabian Ries, Tanja Kazek, …, Laura Armbruster, Markus Wirtz, Zuzana Storchová, Markus Raeschle, Felix Willmund
Cold Spring Harbor Laboratory  ·  16 Dec 2019  ·  doi:10.1101/2019.12.12.874503
The conserved theme of ribosome hibernation: from bacteria to chloroplasts of plants
The conserved theme of ribosome hibernation: from bacteria to chloroplasts of plants
Raphael Trösch, Felix Willmund
Biological Chemistry  ·  01 Feb 2019  ·  doi:10.1515/hsz-2018-0436
The Role of Plastidic Trigger Factor Serving Protein Biogenesis in Green Algae and Land Plants
The Role of Plastidic Trigger Factor Serving Protein Biogenesis in Green Algae and Land Plants
Marina Rohr, Fabian Ries, Claudia Herkt, Vincent Leon Gotsmann, Lisa Désirée Westrich, …, Frederik Sommer, Michael Schroda, Sandro Keller, Torsten Möhlmann, Felix Willmund
Plant Physiology  ·  16 Jan 2019  ·  doi:10.1104/pp.18.01252

2018

Commonalities and differences of chloroplast translation in a green alga and land plants
Commonalities and differences of chloroplast translation in a green alga and land plants
Raphael Trösch, Rouhollah Barahimipour, Yang Gao, Jesús Agustín Badillo-Corona, Vincent Leon Gotsmann, David Zimmer, Timo Mühlhaus, Reimo Zoschke, Felix Willmund
Nature Plants  ·  30 Jul 2018  ·  doi:10.1038/s41477-018-0211-0

2017

Substrates of the chloroplast small heat shock proteins 22E/F point to thermolability as a regulative switch for heat acclimation in Chlamydomonas reinhardtii
Substrates of the chloroplast small heat shock proteins 22E/F point to thermolability as a regulative switch for heat acclimation in Chlamydomonas reinhardtii
Mark Rütgers, Ligia Segatto Muranaka, Timo Mühlhaus, Frederik Sommer, Sylvia Thoms, Juliane Schurig, Felix Willmund, Miriam Schulz-Raffelt, Michael Schroda
Plant Molecular Biology  ·  01 Nov 2017  ·  doi:10.1007/s11103-017-0672-y
Not changes in membrane fluidity but proteotoxic stress triggers heat shock protein expression in <scp><i>Chlamydomonas reinhardtii</i></scp>
Not changes in membrane fluidity but proteotoxic stress triggers heat shock protein expression in Chlamydomonas reinhardtii
Mark Rütgers, Ligia Segatto Muranaka, Miriam Schulz‐Raffelt, Sylvia Thoms, Juliane Schurig, Felix Willmund, Michael Schroda
Plant, Cell & Environment  ·  27 Sep 2017  ·  doi:10.1111/pce.13060
Structural and molecular comparison of bacterial and eukaryotic trigger factors
Structural and molecular comparison of bacterial and eukaryotic trigger factors
Fabian Ries, Yvonne Carius, Marina Rohr, Karin Gries, Sandro Keller, C. Roy D. Lancaster, Felix Willmund
Scientific Reports  ·  06 Sep 2017  ·  doi:10.1038/s41598-017-10625-2

2015

ATP-dependent molecular chaperones in plastids — More complex than expected
ATP-dependent molecular chaperones in plastids — More complex than expected
Raphael Trösch, Timo Mühlhaus, Michael Schroda, Felix Willmund
Biochimica et Biophysica Acta (BBA) - Bioenergetics  ·  01 Sep 2015  ·  doi:10.1016/j.bbabio.2015.01.002

2014

A Direct Regulatory Interaction between Chaperonin TRiC and Stress-Responsive Transcription Factor HSF1
A Direct Regulatory Interaction between Chaperonin TRiC and Stress-Responsive Transcription Factor HSF1
Daniel W. Neef, Alex M. Jaeger, Rocio Gomez-Pastor, Felix Willmund, Judith Frydman, Dennis J. Thiele
Cell Reports  ·  01 Nov 2014  ·  doi:10.1016/j.celrep.2014.09.056
Molecular Chaperone Functions in Plastids
Molecular Chaperone Functions in Plastids
Raphael Trösch, Michael Schroda, Felix Willmund
Plastid Biology  ·  01 Jan 2014  ·  doi:10.1007/978-1-4939-1136-3_13

2013

The Ribosome as a Hub for Protein Quality Control
The Ribosome as a Hub for Protein Quality Control
Sebastian Pechmann, Felix Willmund, Judith Frydman
Molecular Cell  ·  01 Feb 2013  ·  doi:10.1016/j.molcel.2013.01.020
The Cotranslational Function of Ribosome-Associated Hsp70 in Eukaryotic Protein Homeostasis
The Cotranslational Function of Ribosome-Associated Hsp70 in Eukaryotic Protein Homeostasis
Felix Willmund, Marta del Alamo, Sebastian Pechmann, Taotao Chen, Véronique Albanèse, Eric B. Dammer, Junmin Peng, Judith Frydman
Cell  ·  01 Jan 2013  ·  doi:10.1016/j.cell.2012.12.001

2010

Chloroplast DnaJ-like proteins 3 and 4 (CDJ3/4) from <i>Chlamydomonas reinhardtii</i> contain redox-active Fe–S clusters and interact with stromal HSP70B
Chloroplast DnaJ-like proteins 3 and 4 (CDJ3/4) from Chlamydomonas reinhardtii contain redox-active Fe–S clusters and interact with stromal HSP70B
Karolin V. Dorn, Felix Willmund, Christian Schwarz, Christine Henselmann, Thomas Pohl, …, Daniel Veyel, Björn Usadel, Thorsten Friedrich, Jörg Nickelsen, Michael Schroda
Biochemical Journal  ·  29 Mar 2010  ·  doi:10.1042/bj20091412

2008

Assistance for a Chaperone
Assistance for a Chaperone
Felix Willmund, Manuela Hinnenberger, Sabine Nick, Miriam Schulz-Raffelt, Timo Mühlhaus, Michael Schroda
Journal of Biological Chemistry  ·  01 Jun 2008  ·  doi:10.1074/jbc.m708431200

2007

The NH2-terminal Domain of the Chloroplast GrpE Homolog CGE1 Is Required for Dimerization and Cochaperone Function in Vivo
The NH2-terminal Domain of the Chloroplast GrpE Homolog CGE1 Is Required for Dimerization and Cochaperone Function in Vivo
Felix Willmund, Timo Mühlhaus, Maria Wojciechowska, Michael Schroda
Journal of Biological Chemistry  ·  01 Apr 2007  ·  doi:10.1074/jbc.m608854200
The chloroplast HSP70B‐CDJ2‐CGE1 chaperones catalyse assembly and disassembly of VIPP1 oligomers in <i>Chlamydomonas</i>
The chloroplast HSP70B‐CDJ2‐CGE1 chaperones catalyse assembly and disassembly of VIPP1 oligomers in Chlamydomonas
Cuimin Liu, Felix Willmund, Jochen R. Golecki, Sabrina Cacace, Barbara Heß, Christine Markert, Michael Schroda
The Plant Journal  ·  21 Mar 2007  ·  doi:10.1111/j.1365-313x.2007.03047.x

2005

HEAT SHOCK PROTEIN 90C Is a Bona Fide Hsp90 That Interacts with Plastidic HSP70B in <i>Chlamydomonas reinhardtii</i>
HEAT SHOCK PROTEIN 90C Is a Bona Fide Hsp90 That Interacts with Plastidic HSP70B in Chlamydomonas reinhardtii
Felix Willmund, Michael Schroda
Plant Physiology  ·  01 Jul 2005  ·  doi:10.1104/pp.105.063578
J-Domain Protein CDJ2 and HSP70B Are a Plastidic Chaperone Pair That Interacts with Vesicle-Inducing Protein in Plastids 1
J-Domain Protein CDJ2 and HSP70B Are a Plastidic Chaperone Pair That Interacts with Vesicle-Inducing Protein in Plastids 1
Cuimin Liu, Felix Willmund, Julian P. Whitelegge, Susan Hawat, Bettina Knapp, Mukesh Lodha, Michael Schroda
Molecular Biology of the Cell  ·  01 Mar 2005  ·  doi:10.1091/mbc.e04-08-0736